Vol. 12 Issue 3 July - September / 2014
Published on website | Date : 2016-03-24 10:21:09
RELATION OF ANTIMÜLLERIAN, FOLLICULAR STIMULATING HORMONE AND ANTRAL FOLLICLE COUNT ON INTRACYTOPLASMIC SPERM INJECTION OUTCOME IN INFERTILE PATIENTS
Menal F. Farhood, Farqad B. Hamdan, Anam R. Al-Salihi
Background:Studying some of fertility-related hormones is of major benefit to identify the causative factors and to search for an appropriate treatment. Anti-müllerian hormone regarded as quantitative markers for ovarian reserve. Basal follicular stimulating hormone provides a picture of how well the hypothalamic-pituitary-gonadal axis is functioning and is the most commonly used tests for predicting success in intracytoplasmic sperm injection (ICSI) treatment.
Objective:To evaluate the level of serum and follicular fluid antimüllerian hormone, serum follicular stimulating hormone and antral follicle count and its relation to ICSI outcome in infertile patients.
Methods: Seventy four infertile women were selected randomly from those attending the Fertility Centre, Al-Sader Teaching Hospital, Al-Najaf /Iraq. Ultrasound was performed for antral follicle count and their measurement at cycle day 2. Hormonal analysis is done for serum follicular stimulating hormone at cycle day 2 and for serum and follicle fluid antimüllerian hormone at day of ovum pickup.
Result:The fertilization rate was positively correlated with follicular fluid antimüllerian hormone (r = 0.303; P = 0.048) but not with serum follicular stimulating hormone, serum antimüllerian hormone and antral follicle count.
Conclusion: Follicular fluid antimüllerian hormone level was positively correlated with fertilization rate, while serum antimüllerian hormone level does not affect the fertilization rate in ICSI cycle. The basal follicular stimulating hormone level do not relate to fertilization rate, and the same thing regarding antral follicle count.
Keywords:Anti-müllerian hormone, follicular stimulating hormone, antral follicle count, intracytoplasmic sperm injection.
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