Iraqi Journal of Medical Sciences








Vol. 10 Issue 2 April - June / 2012
Published on website | Date : 2016-04-04 20:52:48

THE PROLIFERATIVE PATTERN OF THE VENTRICULAR NEURO-EPITHELIUM OF EMBRYONIC RAT FOURTH VENTRICLE

Ali HA Al-Anbaki


Abstract

Background:Studies have shown that the ventricular neuroepithelium (VN) of the dorsal metencephalonrepresents the site of the cerebellar GABAergic neurons progenitors' production. These studies used different histological techniques but all have provided qualitative information regarding the biosynthesis and cell mitosis.
Objective:Quantifying the proliferative activity of the cells at the (VN) during the embryonic period.
Methods:Nine age groups from day 13 to day 21 albino rat embryos Rattusrattusnorvegicusalbinus were investigated with Ag-NOR staining technique.
Results:There was a statistically significant difference (p<0.01) between cellular activity at different age groups with a maximum proliferative activity on the embryonic day 15.
Conclusion:Ag-NOR staining technique provided a valuable quantitative index of cell proliferation at the (VN) of the developing cerebellum.
Key words:Ventricular Neuroepithelium, Rhombencephalon, Ag-NOR, Quantitative


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