Vol. 11 Issue 2 April - June / 2013
Published on website | Date : 2016-04-03 10:15:57
THE PATTERN OF BACTERIAL PATHOGENS & THEIR ANTIBIOTICS SENSITIVITY AMONG PATIENTS WITH RESPIRATORY TRACT INFECTIONS
Abdul-Munim N Mohammed
Background:Knowing the bacterial pathogens and their antibiotic sensitivity is an important way of establishing a suitable guideline of treatment of infection.
Objectives:To isolate bacterial pathogens from patients with respiratory tract infections (RTI), and to determine the antibiotic sensitivity of isolates.
Methods:Sputum specimens were collected from 145 patients with RTI admitted to Al-Kindy Teaching Hospital from March 2011 to January 2012. Out of these, 88 (60.7%) patients (age rang 17-59 years) had an established bacterial etiology, and of these, 57 (64.8%) were males and 31 (35.2%) females. All isolates were diagnosed according to bacteriological and biochemical standard methods. For identified of antimicrobial susceptibility used from Kirby Bauer method according to (NCCLS).
Results: Klebsiella species and Pseudomonas aeruginosa were the most common isolates among the Gram negative pathogens (26.2% and 11.7% respectively), followed by Escherichia coli and Proteus species, while Streptococcus pneumonia was the most common isolate among the Gram positive organisms, identified in (15.2%) followed by Staphylococcus aureus and Streptococcus pyogenes. High rates of resistance to Amoxicillin and Cephalothin were demonstrated by all bacteria, whereas most isolates were found to be highly sensitive to Amikacin, Ciprofloxacin and Tobramycin. In contrast, Cefotaxim, Tetracyciln, Gentamycin and Erythromicin were less effect against most of isolates.
Conclusions: Klebsiella spp. was the most common pathogens, whereas Streptococcus pneumonia which ranks as second common pathogens from patients with RTI in the present study. Amikacin, Ciprofloxacin and Tobramycin were the most effect antibiotics in vitro against tested bacteria. Conversely, no or less effect of other antibiotic agents was obtained making them not to be considered the drugs of choice in treatment of patients with RTI.
Keywords:Bacterial pathogens, Antibiotics resistance, Patients RTIs.
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